Inhibitor of cathepsins B and L; also thought to inhibit calpain. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with pepstatin A (Cat. Keywords: E 64d, E 64d supplier, lysosomal, proteases, inhibitors, inhibits, cathepsins. Cell-permeable, ethyl ester of Ec. The ester is hydrolyzed by intracellular esterases to produce Ec. Inhibits calpain and cathepsins B, H, and L. Inhibits . Membrane-Permeant Cysteine Protease Inhibitor E64d. S. Eksi,1 B. Czesny,1 G.- J. . or without protease inhibitors, M E64d (Sigma, St Louis, MO), 10 M.

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Ed | CAS | SCBT – Santa Cruz Biotechnology

Volume 2 nanoliter microliter milliliter liter. Not Intended for Diagnostic or Therapeutic Use. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions. Inhibits calpain and cathepsins B, H, and L. PubMed used Ed, a calpain inhibitor, to determine if calpain protease is a possible degradation pathway of ER. Concentration 2 femtomolar picomolar nanomolar micromolar millimolar molar.

Citations for E 64d Citations are publications that use Tocris products. Concentration 1 femtomolar picomolar nanomolar micromolar millimolar molar. Do you know of a great paper that uses E 64d from Tocris? The technical data provided above is for guidance only. Preparing Stock Solutions The following data is based on the product molecular weight Call us Toll Free at What is the solubility of this product?


E-64-d (CAS 88321-09-9)

ED Calpain and cathepsin inhibitor. What is the appearance of the compound? The email address or password you have entered is incorrect. In addition, Zigma has been shown to induce cell cycle arrest during prophase and metaphase in Xenopus embryonic cells. Inhibition of calpain in intact platelets by the thiol protease inhibitor Ed: Skip to main content. Tocris offers the following scientific literature in this area to showcase our products.

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You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more. Inhibits degradation of autophagic cargo inside autophagolysosomes. All trademarks are the property of e64x respective sigm.

Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with pepstatin A Cat. Since degradation was still observed, calpain protease was eliminated as the cause of ER degradation.

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ED – BML-PI – Enzo Life Sciences

A potent inhibitor of thiol protease and cathepsin B, H, and L. Certificate of Analysis Catalog Number sc scA. Fatty acids increase adiponectin secretion through both classical and exosome pathways: Eigma signing up, you indicate that you have read and agree to the terms in our privacy policy.

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Volume 1 nanoliter microliter milliliter liter. Customized Solutions For Your Workflow. Be the first to review E 64d and earn rewards! Citations 1 to 6 of 6 total Display: Tocris products are intended for laboratory xigma use only, unless stated otherwise. Solubility Data Solvent Max Conc. Click on image or enlarge button to enlarge.